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Forbes (July 19, 2023) Kidney function successfully modeled in cell culture
Scientists have made a remarkable breakthrough in kidney research. In a paper published in the journal Biology Communications, a team of researchers at Kyoto University led by Ramin Sadeghian present an innovative approach to building miniature kidney models that closely resemble the structure and function of full-sized human kidneys.
Reuters (July 19, 2023) Regulator says found no animal welfare breaches at Musk firm beyond 2019 incident
The head of the U.S. agency responsible for animal welfare has told lawmakers that it did not find any violations of animal research rules at Elon Musk’s Neuralink beyond a 2019 incident the brain implant company had already reported. Officials with the Department of Agriculture (USDA) conducted a “focused” inspection in response to a complaint about the company’s handling of animal experiments, but identified no compliance breaches, the agency’s secretary Thomas Vilsack wrote to Congressman Earl Blumenauer in a July 14 letter reviewed by Reuters.
Drug Target Review (July 18, 2023) Navigating the challenges and opportunities of AI in drug development and personalized medicine
This article is the second part of Drug Target Review’s Izzy Wood’s discussion with Olivia Cavlan, Chief Corporate Development and Strategy Officer at Alchemab Therapeutics Ltd, exploring the role of AI in target discovery, its applications in personalized medicine, and the evolving landscape of pharmaceutical development.
Open Access Government (July 17, 2023) Artificially grown mini-brains offer new opportunities for neuroscience
In their study published in the Annals of Clinical and Translational Neurology, the University of Michigan researchers utilized human fibronectin. This protein is a native structure for stem cells and is the foundational extracellular matrix for their brain organoids. Supported by a highly porous polymer scaffold, these organoids exhibited enhanced neurogenesis compared to previous studies. Proteomic analysis revealed that the brain organoids developed a cerebral spinal fluid, resembling human adult CSF more accurately than Matrigel-based organoids.
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