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Hi All,
Dropping a quick research roundup below. If you’re looking for a suggestion on where to start, this paper stood out to me: Biomimetic lung-on-a-chip to model virus infection and drug evaluation
In it, the authors provide a broad level review of various different Lung-Chip models and how they’ve been used in the study of viral infections, from Influenza to COVID. The take home? Lung-Chips provide a unique, human-relevant model in which viral pathology and antiviral pharmacology can be readily studied.
Anyway, there are plenty more papers in this list worth giving a read. As always, if I’ve missed a cool paper, drop it in the comments below. Similarly, if you’ve enjoyed these research roundups or found them useful, let me know in the comments. Thanks!
And with that, on to the list:
Organ-Chips and MPS
- Abstract C069: Using a cancer-on-a-chip approach to study the pancreatic cancer tumor microenvironment
- Biomedical Applications of Microfluidic Devices: A Review
- A human kidney and liver organoid-based multi-organ-on-a-chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell-derived extracellular vesicles
- Microfabrication of polydimethylsiloxane–parylene hybrid microelectrode array integrated into a multi-organ-on-a-chip
- Microfluidic trends in drug screening and drug delivery
- Organ-On-A-Chip Database Revealed—Achieving the Human Avatar in Silicon
- A quantitative meta-analysis: Is organ on a chip cell cultures better than static cell cultures?
- Biomimetic lung-on-a-chip to model virus infection and drug evaluation
Organoids, MCTS, and 3D Suspension Cultures
- Impact of alcohol exposure on neural development and network formation in human cortical organoids
- Human multilineage pro-epicardium/foregut organoids support the development of an epicardium/myocardium organoid
- Suspension culture in a rotating bioreactor for efficient generation of human intestinal organoids
- Investigating Mechanical Properties of Suspended Ovarian Cancer Cells and Clusters
- Deciphering the Mechanics of Cancer Spheroid Growth in 3D Environments through Microfluidics Driven Mechanical Actuation
- Workflow for Quantitative Proteomic Analysis of Intestinal Organoids Using SILAC
- A Comparative Systematic Analysis of The Influence of Microplastics on Colon Cells, Mouse and Colon Organoids
- S108 Using forward genetic screens and novel human alveolar organoid models to study surfactant protein C trafficking in heath and disease
- Organoid models of female reproductive tissues to study biology and disease
- T4 Novel lung organoid model reveals crucial role of lung resident mesenchymal stromal cells in COPD pathogenesis
- Establishment of the iPSC line CUIMCi005-A from a patient with Stargardt disease for retinal organoid culture
- Glutathione peroxidase 4 inhibition induces ferroptosis and mTOR pathway suppression in thyroid cancer
- Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1
- Efficient and simple genetic engineering of enteroids using mouse isolated crypts for investigating intestinal functions
- Newer 3D lung models starting to remake research
- Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier
Hydrogels and biomaterial scaffolds
- Biomaterial inks and bioinks for fabricating 3D biomimetic lung tissue: A delicate balancing act between biocompatibility and mechanical printability
- High throughput 3D gel-based neural organotypic model for cellular assays using fluorescence biosensors
- Automation of 3D cell culture using cellulose-based scaffolds
- A Biomimetic Hyaluronic Acid Hydrogel Models Mass Dormancy in Brain Metastatic Breast Cancer Spheroids
Miscellaneous but no less relevant
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