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Hi All,
Dropping this week’s research roundup a bit early this week thanks to a busy day tomorrow. Nonetheless, this feels like a particularly good group. There’re more than a few interesting reviews, and a few articles that are particularly relevant to the ethics of organoid research (if this interests you, definitely hop over to the Frankenstein thread and chime in!)
If you haven’t already done it, be sure to check out our Water Cooler Chat forum as well as our Perspectives forum for some general discussions from the industry.
And with that, on to the list:
Organ-Chips and MPS
- Recent advances and future prospects of functional organ-on-a-chip systems
- Engineering vascular bioreactor systems to closely mimic physiological forces in vitro
- 3D bioprinted cancer models: from basic biology to drug development
- CODA: quantitative 3D reconstruction of large tissues at cellular resolution
- 3D Bioprinting Artificial Respiratory Tract Tissue
- Architected Hydrogels for Functional Tissue Engineering Applications
- Compartmentalized organ-on-a-chip structure for spatiotemporal control of oxygen microenvironments.
- Electrochemical sensing of oxygen metabolism for a three-dimensional cultured model with biomimetic vascular flow
- Integrated experimental-computational analysis of a HepaRG liver-islet microphysiological system for human-centric diabetes research
- Combining human organoids and organ-on-a-chip technology to model intestinal region-specific functionality
Organoids, MCTS, and 3D Suspension Cultures
- OrganoidDB: a comprehensive organoid database for the multi-perspective exploration of bulk and single-cell transcriptomic profiles of organoids
- Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture
- Geometric engineering of organoid culture for enhanced organogenesis in a dish
- How collaboration between bioethicists and neuroscientists can advance research
- AJOB-Neuroscience Top Abstract Award Winners from the 2021 International Neuroethics Society Annual Meeting
- Protective effect of TPP-Niacin on microgravity-induced oxidative stress and mitochondrial dysfunction of retinal epithelia cells
- M1 Macrophages Induce Protumor Inflammation in Melanoma Cells through TNFReNF-kB Signaling
- MYO10-filopodia support basement membranes at pre-invasive tumor boundaries
- Moderated Posters from the United European Gastroenterology Journal
- Activation of environmental carcinogens in human tissue organoid cultures
- Patient-derived organoids to study colorectal cancer evolution and acquired vulnerabilities
- 5-Fluorouracil Promotes the Resistance of Patient-Derived Rectal Cancer Organoids to Irinotecan via Activating the Hedgehog Pathway
- Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system
- Exploring stiffness-dependent roles for YAP in controlling breast cancer cell 3D invasion
- Optimisation of Conditions for the Formation of Spheroids of Head and Neck Squamous Cell Carcinoma Cell Lines for Use as Animal Alternatives
- Water transport regulates nucleus volume, cell density, Young’s modulus, and E-cadherin expression in tumor spheroids
- The tumour microenvironment modulates cancer cell intravasation
- Approaches to investigating metabolism in human neurodevelopment using organoids: insights from intestinal and cancer studies
- HBEGF-TNF induce a complex outer retinal pathology with photoreceptor cell extrusion in human organoids
- Three-Dimensional in Vitro Models: A Promising Tool To Scale-Up Breast Cancer Research
- Organoids as a model to study the human endometrium
- Unravelling the interplay between microbiome, inflammation, metabolic dysregulation and endometrial carcinogenesis
- Patient-Derived Organoids for In Vivo Validation of In Vitro Data
- Once upon a dish: the next frontier in engineering multicellular systems
Hydrogels and biomaterial scaffolds
- Redesigning hydrogel geometry for enhanced organoids
- Tendon Biomimetic PLGA 3D Scaffold Enhances Amniotic Epithelial Stem Cells Biological Capability for Tissue Engineering Applications
- Polymer Thin Film Promotes Tumor Spheroid Formation via JAK2-STAT3 Signaling Primed by Fibronectin-Integrin α5 and Sustained by LMO2-LDB1 Complex
- Bovine and human endometrium-derived hydrogels support organoid culture from healthy and cancerous tissues
- Fabrication of scaffold-free mesenchyme tissue bands by cell self-aggregation technique for potential use in tissue regeneration
- Biomimetic electrospun nanofibrous structures for tissue engineering
- A stabilized CXCL9(74–103)-derived peptide selectively inhibits proliferation, adhesion and metastasis of tumor cells that express high levels of heparan sulfate
Miscellaneous but no less relevant
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