Reply To: Ask Me Anything: Modeling IBD on the Colon Intestine-Chip

[Anthony Heng]

Hi Marianne and Chris,

Have you looked into assessing variability in PBMC recruitment and barrier disruption between different PBMC donors or different intestinal organoid donors? Additionally, have you seen any differences in effects of IBD therapies (i.e. Entyvio, AJM3000, etc.) between different donors (either PBMC or instainal organoid donors)? Thank you!