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Marianne Kanellias

Hi Jackson, thanks for your question. As Chris mentioned we see that the Colon Intestine-Chip supports heterogeneous cell types present in the intestine: absorptive enterocytes (Villin+), goblet cells (Muc2+), enteroendocrine cells (ChgA+), cycling stem cells (Lgr5+) and quiescent stem cells (Bmi1).

This publication assessed the percentage of these populations for three epithelial organoid donors: https://www.cmghjournal.org/article/S2352-345X(21)00145-4/fulltext